The man makes a point. Right noiw you can be ticketed for not wearing your seatbelt. But that ought to be a personal choice, NOT a government mandate. Indeed, there are all sorts of issues relating to driving that ought not to be government concerns. All this has been government “intrusion” that has come over time - surreptitiously.
Liberty dies, one government regulation at a time.
Apollo 11 Moonshot Crew Returns Safely to Earth. Rocket Breaks into Multiple Pieces during Fight, Leaving Debris on Earth and Moon. “Service Module” Mother Ship Burns Up in Atmosphere.
The first twelve launches of the CORONA reconnaissance satellite program (conducted under the cover name “Discoverer”) all failed, and it wasn’t until the 14th launch that pictures were successfully returned from orbit. The first sixRanger lunar impact probes failed. Both CORONA and Ranger were launched by rockets originally developed as ballistic missiles which were considered mature by the time they were used to launch the spacecraft.
The U.S. Supreme Court on Monday declined to hear an appeal by former Minneapolis police officer Derek Chauvin of his conviction for the murder of George Floyd during a 2020 arrest, which sparked widespread protests against police brutality and racism.
The justices turned away Chauvin’s appeal that he filed after a Minnesota appellate court upheld his 2021 murder conviction and rejected his request for a new trial. Chauvin had argued that jury bias and certain rulings by the presiding judge deprived him of his right to a fair trial under the U.S. Constitution’s Sixth Amendment.
Chauvin, who is white, is serving a 22-1/2 year prison sentence for murdering Floyd, who was Black, by kneeling on a handcuffed Floyd’s neck for more than nine minutes during an arrest.
PCA clustering Principal Component Analysis (PCA) plot of 20 populations from 1000 Genomes Project, built using 2 first principal components. The following populations were not used to build the map: ASW = Americans of African Ancestry in SW USA; ACB = African Caribbeans in Barbados; MXL = Mexican Ancestry from Los Angeles USA; GIH = Gujarati Indian from Houston, Texas; STU = Sri Lankan Tamil from the UK; ITU = Indian Telugu from the UK
This is the abstract of the paper:
Background: Principal component analysis (PCA) is a standard method to correct for population stratification in ancestry-specific genome-wide association studies (GWASs) and is used to cluster individuals by ancestry. Using the 1000 genomes project data, we examine how non-linear dimensionality reduction methods such as t-distributed stochastic neighbor embedding (t-SNE) or generative topographic mapping (GTM) can be used to provide improved ancestry maps by accounting for a higher percentage of explained variance in ancestry, and how they can help to estimate the number of principal components necessary to account for population stratification. GTM generates posterior probabilities of class membership which can be used to assess the probability of an individual to belong to a given population - as opposed to t-SNE, GTM can be used for both clustering and classification.
Results: PCA only partially identifies population clusters and does not separate most populations within a given continent, such as Japanese and Han Chinese in East Asia, or Mende and Yoruba in Africa. t-SNE and GTM, taking into account more data variance, can identify more fine-grained population clusters. GTM can be used to build probabilistic classification models, and is as efficient as support vector machine (SVM) for classifying 1000 Genomes Project populations.
Conclusion: The main interest of probabilistic GTM maps is to attain two objectives with only one map: provide a better visualization that separates populations efficiently, and infer genetic ancestry for individuals or populations. This paper is a first application of GTM for ancestry classification models. Our code (hagax8 (Héléna A. Gaspar) · GitHub ancestry_viz) and interactive visualizations (Ancestry Maps) are available online.
OK – these truly are the Crazy Years. Little old me just received a personalized letter from someone claiming to be “Joe Biden” – although the scrawled signature looks like it came from an 80-year old guy suffering from senility problems – asking me to contribute to something called the “Biden Victory Fund”.
Why should anyone contribute? Because Joe is “running for reelection to defend freedom, democracy, our fundamental rights, and equality, and to strengthen the economy”.
As the clincher, the mailing also included an insert from a woman called “Kamala Harris”, although her signature is even worse than “Joe Biden’s”.
Now I am wondering what I did to get myself on this mailing list. Or did Joe pick up such a major contribution from President Xi in San Francisco that he now has the money to mail a personalized request to every taxpayer?
This chart, BTW, would be very different with the same methodology if the non-European samples formed a majority. Then you’d see, say, African or East Asian in the center, with the European samples bunched up in one of the corners. Structure has been developed to address these concerns with a model that’s got better grounding in the actual evolutionary process.
If anyone wants to do this analysis by themselves, here’s a good starting point:
The Idaho National Laboratory (INL), one of the biggest nuclear labs in the US with thousands of employees, has been hacked by the group Sieged Security (stylised SiegeSec). The hackers are self-proclaimed “gay furry hackers” who have posted a sample of the data obtained online, and are threatening to release huge amounts of employee data unless the lab makes a peculiar deal: “We’re willing to make a deal with INL,” says SiegeSec alongside the post, “if they research creating IRL catgirls we will take down this post.”
That is a reference to a long-running meme about furries wanting to create a race of sexy human-mutant cats and, yes, none of those words are in the Bible. The data breach consists of employee addresses, Social Security numbers, birthdates, numbers, and “lots lots more!” The East Idaho News reported it contacted some of the employees in the initial leak, and verified that the information was accurate (thanks, The Register).