Upcoming $101,000,000 Age-reversal X-Prize

I’ve previously discussed the tragic fall from objective-judging-criterion grace by both the Methuselah Mouse Prize (which inspired my approach to the Hutter Prize) and the X-Prize Foundation, after their initial stupendous successes.

As many of us are experiencing age-related cognitive decline, this failure-mode of prize-based philanthropy is decreasingly interesting – but only because we are suffering from cognitive decline. If we were at the peak of critical thinking capacity, and had the same incentive to address age-reversal, the topic of just why there is this relentless trend toward neutralizing prize-based philanthropy would be at the top of our problem-solving priorities.

But, of course, this failure of critical thinking isn’t simply due to age-related cognitive decline. It seems endemic in the way the political economy affects the thinking of philanthropists – otherwise they’d apply the critical thinking skills that made them their money, to this problem.

Yes, coming up with rules that reduce the argument surface of judging criterion is hard. But then, so is making $101M dollars. The RoI on up-front investment in reducing the argument surface of judging criterion without sacrificing desired outcome is enormous and vastly under-estimated by philanthropists.

PS: Here is the history of payouts from the Hutter Prize. Note that their total is on the order of 1/10,000th that of the the proposed Age-reversal X-Prize – and additionally note that the judging criterion is so objective that practically speaking, it could have been totally automated with a few tweaks to the rules.

What is sacrificed in terms of desired outcome (a model of Wikipedia knowledge capable of exhibiting critical thinking)?


An language model capable of such critical thinking would not only clean up Wikipedia’s biases, it would contribute greatly to age-reversal research.

PPS: Notice that Marcus does invite sponsors. Contact him if you’d like to do so.




No blood boy is mentioned. Hard to believe he wouldn’t be using this practice.


Makes you wonder what dictators are doing with the ability to genetically test their populations for the most compatible donors (or compatible young women with whom to breed the most compatible donors).


Is a certain world leader’s puffy face due to fetal stem cell facials, rather than steroidal anti-inflammatories given with chemo?

Our betters keep telling us he has just months to live from the cancer. Either no such severe cancer or something is working.


Zolman Rejuvenation Locations

Coming soon

New York

Interesting mix.


My take is we will soon (1-3 years) learn of some very advanced, very expensive, very difficult procedures that actually work quite well. Have trouble to come up with alternative hypothesis explaining the current longevity epidemic that seems to affect very old and very rich and powerful people.

Kissinger (99), Buffet (93), Soros (93), Munger (99), Murdoch (92) … just a few very prominent examples of individuals whose decline into old age seems to have been decelerating recently. For instance, Murdoch has a new girlfriend.

Speculation is that the “secret” is most likely linked to “young” blood transfusions on a scale which, if disclosed, would make most people recoil in disgust. If none of these individuals leave this mortal coil in the next 5 years, it will become very difficult to pretend to look the other way. The media of course is bought and paid for, but it would be difficult to escape the obvious low likelihood of them all sharing some sort of genetic outlier characteristics that push their healthspan well beyond average.

Seems like if cognition is intact, these type of interventions could be quite effective to extend healthspan.


This is an argument for The Simulation Hypothesis if the VR game we’re all playing is one in which Hell consists of the current insular elites as Demons forever tormenting people so fearful of death that they forever rejuvenate themselves in hopes that Maybe The Next Election will put an end to their torture.


America’s Centenarians: Data From the 1980 Census

That old Census Dept publication stated the US had 14,200 centenarians in 1980, projected to rise to 108,000 in the year 2000. Murdoch may have time for a slew more girlfriends. It is thus not so surprising that a few old men (still part of a much larger cohort than centenarians) are prominent & wealthy.

Is there another factor at work? The longer someone lives, the more money he could accumulate.


There’s been a recent article about some of these newfangled geriatric care procedures:

  • 1 Take all of this stuff.

  • 2 Put it in the blender.

  • 3 Whirr chonka chonka whirr bloppity blup.

  • 4 Bottoms up!

  • 5 ?

  • 6 Have the body of an 18 year old, eternally.

  • ~157788 Learn about telomeres.

  • ~157789 Regret.

I think I’ll stay with the monkey glands, or maybe something stronger.

Barman, another monkey gland!


Or the Genghis Khan formula:

There have been several studies that show ginseng increases overall serum testosterone levels and that ginseng increased testosterone in the saliva, the main issue is that there are a few studies that show this effect does decline over time.

There’s also the downside:

Patient risks associated with ginseng abuse and misuse such as affective disorder, allergy, cardiovascular and renal toxicity, genital organ bleeding, gynecomastia, hepatotoxicity, hypertension, reproductive toxicity, and anticoagulant-ginseng interaction.


What are the brown seeds?

Seems like fear of death driven quests for eternal youth are nothing new. What is different these days is the massive reach the Internet offers.


Agreed… let’s revisit this topic in 5 years’ time.

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They look like European brown lentils, a popular health food.

I’ve eaten a lot of lentils in the last week at CLP.


Is this the medically supervised long duration fasting clinic?

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They do a lot of things at CLP. I was in the medical centre for a hip replacement, but you get meals along the lines of their longevity philosophy there as well as in the more spa-like programmes.

I am not complaining about the food—it was excellent—just quite a bit different from my usual programmer chow.


I found the link I was thinking about - this article is worth skimming even if only for the photos of the meals. They’re not exactly appetizing, but still, quite the native ad


For every study there’s an anti-study